| Identification | Back Directory | [Name]
1,6-Naphthyridin-5(6H)-one, 3-(2-amino[1,2,4]triazolo[1,5-a]pyridin-7-yl)-6-[[2-(cyclopentyloxy)-5-fluorophenyl]methyl]-7,8-dihydro- | [CAS]
2682889-57-0 | [Synonyms]
RIPK1-IN-9
RIPK1-IN-9, 10 mM in DMSO
1,6-Naphthyridin-5(6H)-one, 3-(2-amino[1,2,4]triazolo[1,5-a]pyridin-7-yl)-6-[[2-(cyclopentyloxy)-5-fluorophenyl]methyl]-7,8-dihydro- | [Molecular Formula]
C26H25FN6O2 | [MOL File]
2682889-57-0.mol | [Molecular Weight]
472.51 |
| Hazard Information | Back Directory | [Uses]
RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM)[1]. | [References]
[1] Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1. |
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