| Identification | More | [Name]
8-AZAHYPOXANTHINE | [CAS]
2683-90-1 | [Synonyms]
8-AZAHYPOXANTHINE
4,5-dihydro-1H-triazolo(4,5-d)pyrimidin-4-ol
7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 1,4-dihydro-(9CI)
8-AZAHYPOXANTHINE HYDRATE
7H-1,2,3-Triazolo4,5-dpyrimidin-7-one, 1,4-dihydro-
3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL
1,4-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one | [EINECS(EC#)]
220-244-3 | [Molecular Formula]
C4H3N5O | [MDL Number]
MFCD00005804 | [Molecular Weight]
137.1 | [MOL File]
2683-90-1.mol |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [TSCA ]
TSCA listed | [HS Code ]
2927.00.5000 |
| Hazard Information | Back Directory | [Chemical Properties]
light yellow to light beige fine crystalline | [Uses]
8-Azahypoxanthine is an inhibitor of hypoxanthine-guanine phosphoribosyl transferase (HGPRT). 8-Azahypoxanthine has antitumor activity[1]. | [Definition]
ChEBI:8-azahypoxanthine is a triazolopyrimidine that consists of 1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing an oxo substituent at position 7. It has a role as an antimalarial and an EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor. It is a nucleobase analogue and a member of triazolopyrimidines. | [References]
[1] M H Vaughan, et al. Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro. Exp Cell Res. 1971, 69, 1. DOI:10.1016/0014-4827(71)90314-4 |
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