| Identification | More | [Name]
N-Octyl pyrrolidone | [CAS]
2687-94-7 | [Synonyms]
1-N-OCTYL-2-PYRROLIDONE
1-OCTYL-2-PYRROLIDINONE
1-OCTYL-2-PYRROLIDONE
1-OCTYLPYRROLIDIN-2-ONE
N-OCTYL-2-PYRROLIDONE
N-OCTYL PYRROLIDONE
1-octyl-2-pyrrolidinon
2-Pyrrolidinone,1-octyl-
n-octylpyrrolidinone
1-Octyl-2-pyrsiiolidinone
N-(n-octyl)-pyrrolidin-2-on | [EINECS(EC#)]
403-700-8 | [Molecular Formula]
C12H23NO | [MDL Number]
MFCD00074965 | [Molecular Weight]
197.32 | [MOL File]
2687-94-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
−25 °C(lit.)
| [Boiling point ]
170-172 °C15 mm Hg(lit.)
| [density ]
0.92 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.03-0.08Pa at 20℃ | [refractive index ]
n20/D 1.465(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
clear liquid | [pka]
-0.42±0.20(Predicted) | [color ]
Colorless to Yellow | [Specific Gravity]
0.92 | [Water Solubility ]
1.14-1.25g/L at 20℃ | [BRN ]
1526318 | [InChIKey]
WPPOGHDFAVQKLN-UHFFFAOYSA-N | [LogP]
4.15 at 20℃ | [CAS DataBase Reference]
2687-94-7(CAS DataBase Reference) | [EPA Substance Registry System]
2687-94-7(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
N-Octyl pyrrolidone was synthesized by 2-pyrrolidone and tetrabutylammonium bromide stirred with adding n-octane chloride for 10 h at 90 °C. |
| Safety Data | Back Directory | [Hazard Codes ]
C,N | [Risk Statements ]
R34:Causes burns.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S1/2:Keep locked up and out of the reach of children . | [RIDADR ]
UN 3267 8/PG 2
| [WGK Germany ]
2
| [RTECS ]
UY5896000
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29339900 | [Toxicity]
LD50 orl-rat: 2050 mg/kg FCTOD7 26,475,88 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless or slightly yellow clear liquid | [Uses]
N-Octyl pyrrolidone(NOP) is a highly efficient and selective solvent, which can be used in the recovery of organic raw materials, the refining of lubricating oils, and the solvent for polymers and polymerization reactions; It is also widely used in chemical synthesis reactions. | [Definition]
ChEBI:N-Octyl-2-pyrrolidone is a N-alkylpyrrolidine. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 57, p. 3328, 1992 DOI: 10.1021/jo00038a019 | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 59, p. 6378, 1994 DOI: 10.1021/jo00100a046 | [General Description]
1-Octyl-2-pyrrolidone is a permeation enhancer and its effect in transport of steroidal permeants across hairless mouse skin was investigated via a parallel pathway skin model. | [Flammability and Explosibility]
Nonflammable | [Safety Profile]
Moderately toxic by ingestion. Asevere skin and eye irritant. A corrosive. Combustibleliquid. When heated to decomposition it emits toxic fumesof NOx. |
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