| Identification | Back Directory | [Name]
thonningianin A | [CAS]
271579-11-4 | [Synonyms]
thonningianin A
Pinocembrin dihydrochalcone 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-beta-D-glucoside
1-Propanone, 1-[4-[[4,6-O-[[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-diyl]dicarbonyl]-3-O-(3,4,5-trihydroxybenzoyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-phenyl- | [Molecular Formula]
C42H34O21 | [MDL Number]
MFCD30725006 | [MOL File]
271579-11-4.mol | [Molecular Weight]
874.71 |
| Chemical Properties | Back Directory | [Boiling point ]
1364.1±65.0 °C(Predicted) | [density ]
1.89±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
6.80±0.40(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities[1][2]. | [Definition]
ChEBI: Thonningianin A is a tannin. It has a role as a metabolite. | [storage]
4°C, protect from light | [References]
[1] Gyamfi MA, et al. Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea. Biochem Pharmacol. 2002 May 1;63(9):1725-37. DOI:10.1016/s0006-2952(02)00915-2
[2] Zhang TT, et al. Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells. Food Funct. 2015 Aug;6(8):2588-97. DOI:10.1039/c5fo00388a |
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