ChemicalBook--->CAS DataBase List--->271579-12-5

271579-12-5

271579-12-5 Structure

271579-12-5 Structure
IdentificationBack Directory
[Name]

thonningianin B
[CAS]

271579-12-5
[Synonyms]

thonningianin B
1-Propanone, 1-[4-[[4,6-O-[[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-diyl]dicarbonyl]-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-phenyl-
[Molecular Formula]

C35H30O17
[MOL File]

271579-12-5.mol
[Molecular Weight]

722.61
Chemical PropertiesBack Directory
[Boiling point ]

1239.4±65.0 °C(Predicted)
[density ]

1.670±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

6.80±0.40(Predicted)
[color ]

Light yellow to light brown
Hazard InformationBack Directory
[Uses]

Thonningianin B is an antioxidant and an autophagy enhancer[1][2].
[References]

[1] Ohtani II, et al. Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea. J Nat Prod. 2000 May;63(5):676-9. DOI:10.1021/np990396w
[2] Zhou XG, et al. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. Inflamm Regen. 2022 Aug 3;42(1):25. DOI:10.1186/s41232-022-00209-7
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