2735713-77-4

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2735713-77-4 Structure

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[Name] INDEX NAME NOT YET ASSIGNED
[CAS] 2735713-77-4
[Synonyms] SGC agonist 2
[Molecular Formula] C23H17F2N7O2
[MOL File] 2735713-77-4.mol
[Molecular Weight] 461.43

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[Uses] SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031)[1].
[References] [1] Fuyu Luo, et al. Pyrimidine tricyclic compounds and their applications. Patent WO2021219088A1.

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