| Identification | Back Directory | [Name]
1H-Indole-6-methanol, 4-[4-[1-(5-fluoro-3-pyridinyl)-3,5-dimethyl-1H-pyrazol-4-yl]-6-[(3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]- | [CAS]
2746446-99-9 | [Synonyms]
ATR-IN-6
1H-Indole-6-methanol, 4-[4-[1-(5-fluoro-3-pyridinyl)-3,5-dimethyl-1H-pyrazol-4-yl]-6-[(3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]- | [Molecular Formula]
C28H28FN7O2 | [MOL File]
2746446-99-9.mol | [Molecular Weight]
513.57 |
| Hazard Information | Back Directory | [Uses]
ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22)[1]. | [References]
[1] Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent WO2021233376A1. |
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