| Identification | Back Directory | [Name]
Thalidomide-O-amide-C5-NH2 TFA | [CAS]
2748161-83-1 | [Synonyms]
Thalidomide-O-amide-C5-NH2 TFA
N-(5-Aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-amide-C5-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | [IC 50]
Cereblon | [References]
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277 |
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Bide Pharmatech Ltd.
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400-1647117 13681763483 |
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https://www.bidepharm.com/ |
| Company Name: |
TargetMol
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www.targetmol.cn/ |
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