| Identification | Back Directory | [Name]
Thalidomide-O-amido-C3-NH2 (TFA) | [CAS]
2022182-58-5 | [Synonyms]
Thalidomide-O-amido-C3-NH2
Thalidomide-O-amido-C3-NH2 (TFA)
Pomalidomide Related Compound 3 Triflate
Cereblon Ligand-Linker Conjugates 16 TFA
E3 Ligase Ligand-Linker Conjugates 52 (TFA)
N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
N-(3-aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide(TFA)
N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
N-(3-Aminopropyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetic acid salt | [Molecular Formula]
C20H21F3N4O8 | [MDL Number]
MFCD32215305 | [MOL File]
2022182-58-5.mol | [Molecular Weight]
502.4 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | [IC 50]
Cereblon | [References]
[1] Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. DOI:10.1016/j.bmcl.2016.09.048 |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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