| Chemical Properties | Back Directory | [Boiling point ]
823.6±65.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
Light yellow to yellow | [InChIKey]
QBNKTDRYOJRHQN-UHFFFAOYSA-N | [SMILES]
C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCOCCC(=O)O |
| Hazard Information | Back Directory | [Uses]
DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1]. | [IC 50]
Non-cleavable Linker | [References]
[1] Shih-Hsien Chuang, et al. Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof. WO2021248048A2. |
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