| Chemical Properties | Back Directory | [Melting point ]
199-200 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1)) | [Boiling point ]
527.0±33.0 °C(Predicted) | [density ]
1.05±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Chloroform: 10 mg/ml,DMF: 1 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
3-O-Acetylbetulin aldehyde is a derivative of Betulin (HY-N0083). 3-O-Acetylbetulin aldehyde has anticancer activity[1][2]. | [Biological Activity]
3-Acetyl betulinaldehyde is a triterpene and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in A. japonica.1 It is an intermediate in the synthesis of 3-acetylbetulinic acid, as well as various lupine and germanicane triterpenes and saponins with anticancer activity.2 | [storage]
-20°C | [References]
1.Tung, N.H., Kwon, H.-J., Kim, J.-H., et al.An anti-influenza component of the bark of Alnus japonicaArch. Pharm. Res.33(3)363-367(2010)
2.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007)
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ChemeGen
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18818260767 |
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https://www.chemegen.com |
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