| Identification | Back Directory | [Name]
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[[2-methyl-4-(trifluoromethyl)-5-thiazolyl]carbonyl]- | [CAS]
2757552-21-7 | [Synonyms]
Transketolase-IN-2
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[[2-methyl-4-(trifluoromethyl)-5-thiazolyl]carbonyl]- | [Molecular Formula]
C18H9F3N2O3S | [MOL File]
2757552-21-7.mol | [Molecular Weight]
390.34 |
| Chemical Properties | Back Directory | [Boiling point ]
570.5±60.0 °C(Predicted) | [density ]
1.585±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-1.87±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Transketolase-IN-2 (compound 4w) is a potent Transketolase inhibitor. Transketolase-IN-2 shows strong inhibition of Digitaria sanguinalis and Amaranthus retroflexus (over 90% at 200 mg/L and about 80% at 100 mg/L). Transketolase-IN-2 can be used in studies of weed control[1]. | [References]
[1] Wang YE, et al. Design, Synthesis, and Herbicidal Activity of Naphthalimide-Aroyl Hybrids as Potent Transketolase Inhibitors. J Agric Food Chem. 2022 Oct 12;70(40):12819-12829. DOI:10.1021/acs.jafc.2c04533 |
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