| Identification | Back Directory | [Name]
4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [CAS]
2758431-96-6 | [Synonyms]
4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [Molecular Formula]
C17H18N6O4 | [MOL File]
2758431-96-6.mol | [Molecular Weight]
370.37 |
| Hazard Information | Back Directory | [Uses]
Pomalidomide 4'-alkylC4-azide (Compound 2) is an azide compound containing a MIDI group and is one of the compounds used to construct a library of MIDI azide compounds. Pomalidomide 4'-alkylC4-azide can be used to develop research on PROTAC degraders[1]. | [Biological Activity]
Pomalidomide 4'-alkylC4-azide is a functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal azide ready for conjugation to a target protein ligand. | [storage]
Store at -20°C | [References]
[1] Liu H,et al. Construction of an IMiD-based azide library as a kit for PROTAC research[J]. Organic & Biomolecular Chemistry, 2021, 19(1): 166-170. DOI:10.1039/d0ob02120b |
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