| Identification | Back Directory | [Name]
Benzoic acid, 3-[[[4-oxo-2-[4-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butoxy]phenyl]-4H-1-benzopyran-3-yl]oxy]methyl]-, methyl ester | [CAS]
2760674-72-2 | [Synonyms]
Ac32Az19
Benzoic acid, 3-[[[4-oxo-2-[4-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butoxy]phenyl]-4H-1-benzopyran-3-yl]oxy]methyl]-, methyl ester | [Molecular Formula]
C37H33N3O6 | [MOL File]
2760674-72-2.mol | [Molecular Weight]
615.67 |
| Chemical Properties | Back Directory | [Boiling point ]
826.3±75.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
1.46±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Ac32Az19 is a potent, nontoxic, and highly selective BCRP inhibitor with an EC50 value of 13 nM in the
BCRP-overexpressed HEK293/R2 cells. | [References]
[1] Wong ILK, et al. Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2). J Med Chem. 2021 Oct 14;64(19):14311-14331. DOI:10.1021/acs.jmedchem.1c00779 |
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