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2763386-05-4

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2763386-05-4 Structure

2763386-05-4 Structure
IdentificationBack Directory
[Name]

NA
[CAS]

2763386-05-4
[Synonyms]

[Molecular Formula]

C22H24ClFN6O2
[MOL File]

2763386-05-4.mol
[Molecular Weight]

458.92
Chemical PropertiesBack Directory
[Boiling point ]

699.0±55.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

11.60±0.40(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

RET-IN-7 demonstrates potent in vitro RET kinase inhibition and robust in vivo efficacy in RET-driven tumor xenografts upon multiday dosing in mice.
[References]

[1] Mathison CJN, et al. Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors. ACS Med Chem Lett. 2021 Nov 6;12(12):1912-1919. DOI:10.1021/acsmedchemlett.1c00450
2763386-05-4 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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