| Identification | Back Directory | [Name]
Benzenesulfonamide, N,N-dipropyl-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]- | [CAS]
2770297-66-8 | [Synonyms]
EG-2184
Benzenesulfonamide, N,N-dipropyl-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]- | [Molecular Formula]
C15H19F6NO3S | [MOL File]
2770297-66-8.mol | [Molecular Weight]
407.37 |
| Chemical Properties | Back Directory | [Boiling point ]
426.3±55.0 °C(predicted) | [density ]
1.351±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
8.69±0.15(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research[1]. | [IC 50]
Panx1 | [References]
[1] Kwok CHT, et al. Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry. Nat Commun. 2024 Jul 24;15(1):6264. DOI:10.1038/s41467-024-50657-7 |
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