| Identification | More | [Name]
L-Glutamic acid dibenzyl ester 4-toluenesulfonate | [CAS]
2791-84-6 | [Synonyms]
GLU(OBZL)-OBZL TOS
GLUTAMIC ACID(OBZL)-OBZL P-TOSYLATE
H-GLU(OBZL)-OBZL 4-TOSYLATE
H-GLU(OBZL)-OBZL P-TOSYLATE
H-GLU(OBZL)-OBZL TOS
H-GLU(OBZL)-OBZL TOSOH
L-GLUTAMIC ACID ALPHA,GAMMA-DIBENZYL ESTER 4-TOLUENESULFONATE SALT
L-GLUTAMIC ACID ALPHA,GAMMA-DIBENZYL ESTER MONOTOSYLATE
L-GLUTAMIC ACID ALPHA,GAMMA-DIBENZYL ESTER P-TOLUENESULFONATE SALT
L-GLUTAMIC ACID-ALPHA,GAMMA-DIBENZYL ESTER P-TOSYLATE
L-GLUTAMIC ACID ALPHA,GAMMA-DIBENZYL ESTER TOSYLATE
L-GLUTAMIC ACID DIBENZYL ESTER 4-TOLUENESULFONATE SALT
L-GLUTAMIC ACID DIBENZYL ESTER-P-TOSYLATE
L-GLUTAMIC ACID GAMMA-BENZYL ESTER ALPHA-BENZYL ESTER TOSYLATE
O,O'-dibenzyl-L-glutamine toluene-p-sulphonate
Glu(OBzl)-OBzl·TosOH
GLU(OBZL)-OBZLOSOH
H-Glu(Obzl)-Obzlosoh
O,O'-Dibenzyl-L-glutamine
L-Glutamic acid dibenzyl ester 4-toluenesulfonate | [EINECS(EC#)]
220-522-4 | [Molecular Formula]
C26H29NO7S | [MDL Number]
MFCD00038980 | [Molecular Weight]
499.58 | [MOL File]
2791-84-6.mol |
| Hazard Information | Back Directory | [Description]
L-Glutamic acid dibenzyl ester tosylate is a glutamic acid derivative. | [Uses]
Dibenzyl L-glutamate tosylate is a glutamic acid derivative[1]. | [Synthesis]
General procedure for the synthesis of L-glutamic acid bisbenzyl ester p-toluenesulfonate from L-glutamic acid, 4-methylphenylsulfonic acid and benzyl alcohol: 29.4 g (0.2 mol) of L-(+)-glutamic acid, 40 g (0.23 mol) of p-toluenesulfonic acid and 80 mL of benzyl alcohol were dissolved in 500 mL of toluene. 11 mL of water was separated by refluxing under nitrogen protection. Refluxing was continued for 3 hours, followed by evaporation and removal of 150 mL of liquid. The reaction solution was cooled to 50°C and then poured into a beaker containing 600 mL of petroleum ether and stirred for 1 hour. The precipitate was collected by filtration. The filter cake was dissolved in 280 mL of 95% ethanol by heating, and after the heating was stopped, the solution was cooled overnight. The precipitate was collected by filtration and dried under vacuum to give 61 g of L-(+)-glutamic acid bisbenzyl ester p-toluenesulfonate (Compound 1). | [References]
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368 |
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