| Identification | Back Directory | [Name]
(2S)-N-[(2S,3S)-1-(8-Amino-1-oxooctyl)-2,3,4,5-tetrahydro-5-[(2-methoxy-1-naphthalenyl)methyl]-2-methyl-4-oxo-1H-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide | [CAS]
2803617-91-4 | [Synonyms]
(2S)-N-[(2S,3S)-1-(8-Amino-1-oxooctyl)-2,3,4,5-tetrahydro-5-[(2-methoxy-1-naphthalenyl)methyl]-2-methyl-4-oxo-1H-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide | [Molecular Formula]
C34H45N5O4 | [MOL File]
2803617-91-4.mol | [Molecular Weight]
587.75 |
| Chemical Properties | Back Directory | [Boiling point ]
869.3±65.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
13.33±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP). | [References]
[1] den Besten W, et al. Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein. J Am Chem Soc. 2021 Jul 21;143(28):10571-10575. DOI:10.1021/jacs.1c05269 |
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