ChemicalBook--->CAS DataBase List--->2832-19-1

2832-19-1

2832-19-1 Structure

2832-19-1 Structure
IdentificationMore
[Name]

N-Methylolchloroacetamide
[CAS]

2832-19-1
[Synonyms]

2-CHLORO-N-(HYDROXYMETHYL)ACETAMIDE
N1-HYDROXYMETHYL-2-CHLOROACETAMIDE
N-HYDROXYMETHYL-2-CHLOROACETAMIDE
N-HYDROXYMETHYLCHLOROACETAMIDE
N-METHYLOLCHLOROACETAMIDE
TIMTEC-BB SBB004273
2-chloro-N-(hydroxymethyl)acetamid
2-chloro-n-(hydroxymethyl)-acetamid
2-chloro-n-hydroxymethyl-acetamid
chloracetamide-n-metholol
n-methylol-chloracetamide
N-Hydromethyl-2-Chloroacetamide
Acetamide, 2-chloro-N-(hydroxymethyl)-
2-Chioro-N-hydroxymethylacetamide
METHYLOLCHLOROACETAMIDE
CHLOROACETAMIDEN-METHYLOL
CHLOROHYDROXYMETHYLACETAMIDE
N-(Hydroxymethyl)-2-chloracetamide
N-Methylol-2-chloroacetamide
Grotan HD
[EINECS(EC#)]

220-598-9
[Molecular Formula]

C3H6ClNO2
[MDL Number]

MFCD00021961
[Molecular Weight]

123.54
[MOL File]

2832-19-1.mol
Chemical PropertiesBack Directory
[Appearance]

White or almost white crystalline powder
[Melting point ]

100-105 °C(lit.)
[Boiling point ]

374.0±27.0 °C(Predicted)
[density ]

1.2776 (rough estimate)
[refractive index ]

1.5000 (estimate)
[storage temp. ]

0-6°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.63±0.46(Predicted)
[color ]

White to Off-White
[Water Solubility ]

Very soluble in water. Poorly soluble in aliphatic hydrocarbons.
[Sensitive ]

Hygroscopic
[BRN ]

1811765
[InChI]

InChI=1S/C3H6ClNO2/c4-1-3(7)5-2-6/h6H,1-2H2,(H,5,7)
[InChIKey]

TXNSZCSYBXHETP-UHFFFAOYSA-N
[SMILES]

C(NCO)(=O)CCl
[CAS DataBase Reference]

2832-19-1(CAS DataBase Reference)
[EPA Substance Registry System]

2832-19-1(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)
GHS05
[Signal word ]

Danger
[Hazard statements ]

H314
[Precautionary statements ]

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
R43:May cause sensitization by skin contact.
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 3261 8/PG 2
[WGK Germany ]

3
[RTECS ]

AB5733000
[TSCA ]

Yes
[HazardClass ]

8
[PackingGroup ]

Ⅱ
[HS Code ]

29241990
[Storage Class]

8A - Combustible corrosive hazardous materials
[Hazard Classifications]

Eye Dam. 1
Skin Corr. 1B
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Chloro-N-(hydroxymethyl)acetamide(2832-19-1).msds
Hazard InformationBack Directory
[Chemical Properties]

White or almost white crystalline powder
[Uses]

2-Chloro-N-(hydroxymethyl)acetamide (N-hydroxymethylchloroacetamide) may be used as a reagent in the synthesis of 1-(aminomethyl)-2-methoxynaphthalene hydrochloride and as a amidomethylating reagent for N,N-dialkylanilines (Tscherniac-Einhorn reaction).
[Uses]

An organic building block. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals. As dyestuff intermediate .
[Uses]

N-Methylolchloro-acetamide is a preservative in cooling fluids and cosmetics.
[General Description]

2-Chloro-N-(hydroxymethyl)acetamide (N-methylolchloracetamide) is a N-hydroxymethyl derivative of chloroacetamide. One of the method reported for its synthesis is by the reaction of 2-chloracetamide with formaldehyde. It has been reported to be a formaldehyde releaser and an infrequent sensitizer to formaldehyde contact allergy. Influence of short and prolonged exposure of 2-chloro-N-(hydroxymethyl)acetamide (as formaldehyde donor/releaser) on lymph node responses has been investigated. It has high biocide action and is utilized as preservative.
Spectrum DetailBack Directory
[Spectrum Detail]

N-Methylolchloroacetamide(2832-19-1)1HNMR
N-Methylolchloroacetamide(2832-19-1)IR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

2-Chloro-N-(hydroxymethyl)acetamide, 98%(2832-19-1)
[Sigma Aldrich]

2832-19-1(sigmaaldrich)
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