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JMV-1645 is a potent and selective B1 bradykinin receptor antagonist with a Ki value of 0.023 nM on the human cloned B1 receptor. JMV-1645 can be utilized in trauma and infection research[1]. | [IC 50]
Bradykinin B1 Receptor (B1R): 0.023 nM (Ki) | [References]
[1] Bedos P, et al. A rational approach to the design and synthesis of a new bradykinin B(1) receptor antagonist. J Med Chem. 2000 Jun 15;43(12):2387-94. DOI:10.1021/jm990962k |
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