| Identification | More | [Name]
3,4-Epoxytetrahydrofuran | [CAS]
285-69-8 | [Synonyms]
3,4-EPOXYTETRAHYDROFURAN
3,6-DIOXABICYCLO[3.1.0]HEXANE
3,4-EPOXYTETRAHYDROFURAN 96%
3,4-Epoxytetrahydrofurane
3,4-Epoxytetrahydrofuran, 98 %
3,4-Epoxy-THF
3,4-Diepoxytetrahydrofuran | [EINECS(EC#)]
206-006-1 | [Molecular Formula]
C4H6O2 | [MDL Number]
MFCD00800639 | [Molecular Weight]
86.09 | [MOL File]
285-69-8.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow liquid | [Boiling point ]
44°C 10mm | [density ]
1.237 | [refractive index ]
1.445-1.449
| [Fp ]
>38℃ | [storage temp. ]
0-6°C | [form ]
Liquid | [color ]
Clear yellow | [Water Solubility ]
MODERATELY SOLUBLE | [InChI]
InChI=1S/C4H6O2/c1-3-4(6-3)2-5-1/h3-4H,1-2H2 | [InChIKey]
AIUTZIYTEUMXGG-UHFFFAOYSA-N | [SMILES]
C12C(O1)COC2 | [CAS DataBase Reference]
285-69-8(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
3,6-Dioxabicyclo[3.1.0]hexane was a reagent used in making various degradable polymers from epoxides using a versatile dinuclear chromium catalyst. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R10:Flammable. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
1993 | [Hazard Note ]
Irritant | [HazardClass ]
3 | [PackingGroup ]
Ⅲ | [HS Code ]
29321900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow liquid | [Synthesis]
Step 1: 85% m-chloroperoxybenzoic acid (mCPBA) (18.86 g, 0.093 mol) was slowly added to 150 mL of dichloromethane solution containing 2,5-dihydrofuran (5.04 g, 0.072 mol) at 0°C in an ice-water bath. The reaction mixture was stirred at room temperature for 48 hours. After completion of the reaction, the precipitate was removed by filtration. The filtrate was washed sequentially with saturated aqueous sodium bicarbonate, water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give a mixture of white solid and yellow oil (5.24 g, 84.6% yield). | [References]
[1] Patent: WO2008/33562, 2008, A2. Location in patent: Page/Page column 53
[2] Patent: US2009/76005, 2009, A1. Location in patent: Page/Page column 23
[3] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8467 - 8487
[4] Patent: US5374416, 1994, A
[5] Patent: US2009/30212, 2009, A1. Location in patent: Page/Page column 15-16 |
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