| Chemical Properties | Back Directory | [Boiling point ]
550.5±50.0 °C(predicted) | [density ]
1.348±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
Chloroform: Soluble
Methanol: Slightly Soluble | [form ]
Solid | [pka]
6.72±0.10(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy[1]. | [References]
[1] Shijie Fan, et al. Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26105-26114. DOI:10.1002/anie.202109464 |
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| Company Name: |
Wuhan Topule
|
| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
|