| Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-[5-[[(3R,6S)-1-ethyl-6-methyl-3-piperidinyl]oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- | [CAS]
2879250-73-2 | [Synonyms]
2,6-Piperidinedione, 3-[5-[[(3R,6S)-1-ethyl-6-methyl-3-piperidinyl]oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- | [Molecular Formula]
C21H27N3O4 | [MOL File]
2879250-73-2.mol | [Molecular Weight]
385.46 |
| Chemical Properties | Back Directory | [Boiling point ]
627.9±55.0 °C(predicted) | [density ]
1.242±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
10.78±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
WIZ degrader 5 (compound 41) is a WIZ degrader and induces the degradation of WIZ with maximum degradation of 88.6% in 293T cells. WIZ degrader 5 can be used for study of sickle cell disease
[1]. | [References]
[1] Simone BONAZZI, et al. 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and medical uses thereof. WO2022254362A1. 2022-12-08. |
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