| Chemical Properties | Back Directory | [Boiling point ]
653.2±55.0 °C(predicted) | [density ]
1.262±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
12.55±0.23(predicted) |
| Hazard Information | Back Directory | [Uses]
HDAC/NAMPT-IN-1 (compound 39h) is a dual inhibitor of HDAC and NAMPT with IC50 values of 0.72-37081 nM and 1618 nM[1]. | [References]
[1] Kairui Yue, et al. HDAC/NAMPT dual inhibitors overcome initial drug-resistance in p53-null leukemia cells. Eur J Med Chem. 2024. DOI:10.1016/j.ejmech.2024.116127 |
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