| Identification | Back Directory | [Name]
Glp-Asn-Pro-AMC | [CAS]
291752-43-7 | [Synonyms]
Glp-Asn-Pro-AMC
L-Prolinamide, 5-oxo-L-prolyl-L-asparaginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C24H27N5O7 | [MOL File]
291752-43-7.mol | [Molecular Weight]
497.5 |
| Chemical Properties | Back Directory | [Boiling point ]
1016.689±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.439±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
12.568±0.20(predicted) | [color ]
White to off-white | [Sequence]
{Glp}-Asn-Pro-{AMC} |
| Hazard Information | Back Directory | [Uses]
Glp-Asn-Pro-AMC is an inhibitor of thyrotropin-releasing hormone degrading enzyme (TRH-DE) with a Ki value of 0.97 μM[1]. | [References]
[1] Charli JL, et al. The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target? Front Pharmacol. 2020 May 8;11:640. DOI:10.3389/fphar.2020.00640 |
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