| Identification | Back Directory | [Name]
(E)-2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid | [CAS]
292640-28-9 | [Synonyms]
CK2/PIM1-IN-1
CK2/PIM1 IN 1,CK2/PIM1IN1,CK-2/PIM1-IN-1
Benzoic acid, 2-[5-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]-2-furanyl]-
(E)-2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid | [Molecular Formula]
C15H9NO4S2 | [MDL Number]
MFCD01832338 | [MOL File]
292640-28-9.mol | [Molecular Weight]
331.37 |
| Hazard Information | Back Directory | [Uses]
CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1, with IC50s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively. CK2/PIM1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders[1]. | [IC 50]
CK2: 3.787 μM (IC50); PIM1: 4.327 μM (IC50) | [References]
[1] Mustapha Haddach, et al. Rhodanines and related heterocycles as kinase inhibitors. WO2010148351A1. |
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