| Identification | More | [Name]
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE | [CAS]
2933-29-1 | [Synonyms]
AURORA 11604
AKOS B000350
AKOS BB-9229
ASISCHEM D48930
AKOS BBS-00002178
TIMTEC-BB SBB000119
ART-CHEM-BB B000350
IFLAB-BB F1040-0006
CHEMBRDG-BB 3000350
OTAVA-BB BB7010240510
2-Amino-4,5,6,7-tetrahydrobenzothiazole
4,5,6,7-Tetrahydro-2-aminobenzothiazole
2-BenzothiazolaMine, 4,5,6,7-tetrahydro-
4,5,6,7-Tetrahydrobenzo[d]thiazol-2-aMine
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE
4,5,6,7-Tetrahydrobenzothiazoyl-2-ylamine
BENZOTHIAZOLE, 4,5,6,7-TETRAHYDRO-2-AMINO-
2-Amino-4,5,6,7-tetrahydrobenzothiazole 97%
4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-AMINE
2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazole
4,5,6,7-TETRAHYDRO-1,3-BENZOTHIAZOL-2-YLAMINE
4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine(SALTDATA: FREE) | [Molecular Formula]
C7H10N2S | [MDL Number]
MFCD00022851 | [Molecular Weight]
154.23 | [MOL File]
2933-29-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [RTECS ]
DL6425000 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2934208090 | [Toxicity]
mouse,LD50,intravenous,72mg/kg (72mg/kg),Acta Pharmaceutica Suecica. Vol. 8, Pg. 49, 1971. |
| Hazard Information | Back Directory | [Synthesis Reference(s)]
Tetrahedron, 37, p. 2607, 1981 DOI: 10.1016/S0040-4020(01)98964-1 | [Synthesis]
GENERAL METHODS: A mixture of cyclohexanone (2 mmol), thiourea (3 mmol) and iodine (2 mmol) was reacted by refluxing in ethanol in the presence of 0.03 g of nano-chitosan catalyst. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent was petroleum ether to ethyl acetate in 4:1 volume ratio). Upon completion of the reaction, the catalyst was removed by simple filtration. After evaporation to remove the solvent, the crude product was dissolved in boiling water and extracted with ether (3 x 30 mL). Subsequently, the pH of the aqueous phase was adjusted to 8 with ammonia to precipitate the solid product. Finally, pure 2-amino-4,5,6,7-tetrahydrobenzothiazole was obtained by recrystallization from ethanol-water mixed solvent. | [References]
[1] Catalysis Communications, 2016, vol. 77, p. 108 - 112
[2] Patent: KR2017/23387, 2017, A. Location in patent: Paragraph 0054; 0056; 0057
[3] Chemical and Pharmaceutical Bulletin, 2004, vol. 52, # 5, p. 634 - 637
[4] Journal of Medicinal Chemistry, 2009, vol. 52, # 3, p. 718 - 725
[5] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986, vol. 25, p. 966 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE(2933-29-1)MS
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE(2933-29-1)1HNMR
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE(2933-29-1)1HNMR
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE(2933-29-1)IR1
4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE(2933-29-1)IR2
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