| Identification | Back Directory | [Name]
9-Octadecenoic acid (9Z)-, 6-[[3-(dimethylamino)propyl][(9Z)-1-oxo-9-octadecen-1-yl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl ester | [CAS]
2953044-98-7 | [Synonyms]
Lipid 119-23
9-Octadecenoic acid (9Z)-, 6-[[3-(dimethylamino)propyl][(9Z)-1-oxo-9-octadecen-1-yl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl ester | [Molecular Formula]
C58H105N3O4 | [MOL File]
2953044-98-7.mol | [Molecular Weight]
908.47 |
| Chemical Properties | Back Directory | [Boiling point ]
900.0±65.0 °C(predicted) | [density ]
0.99±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
Chloroform: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml | [pka]
14.79±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
Lipid 119-23 is an ionizable cationic lipid which can be utilized in the formation of lipid nanoparticles and the delivery of mRNA. Lipid 119-23 exhibits an enhanced capability to express functional mCre in several categories of immune cells, spanning the liver, spleen and lung[1]. | [References]
[1] Li B, et al. Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry. Nat Mater. 2024 Jul;23(7):1002-1008. DOI:10.1038/s41563-024-01867-3 |
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| Company Name: |
DC Chemicals
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| Telephone: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0_EN.htm |
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