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295350-45-7

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295350-45-7 Structure

295350-45-7 Structure
IdentificationBack Directory
[Name]

Ozarelix
[CAS]

295350-45-7
[Synonyms]

D 63153
D-63153
Ozarelix
Ozarrelix
Ozarelix Acetate
AC-D-2-NAL-D-4-CPA-D-3-PAL-SER-N-ME-TYR-D-HCI-NLE-ARG-PRO-D-ALA-NH2
Ac-D-2-Nal-D-4-Cpa-D-3-Pal-Ser-N-Me-Tyr-D-Hci-Nle-Arg-Pro-D-Ala-NH2 acetate salt
N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-N6-(aminocarbonyl)-D-lysyl-L-norleucyl-L-arginyl-L-prolyl-D-alaninamide
D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-N6-(aminocarbonyl)-D-lysyl-L-norleucyl-L-arginyl-L-prolyl-
[Molecular Formula]

C72H96ClN17O14
[MOL File]

295350-45-7.mol
[Molecular Weight]

1459.09
Chemical PropertiesBack Directory
[density ]

1.40
[pka]

9.82±0.15(Predicted)
[InChIKey]

KATZUZNTRINHDT-HALMFYTRSA-N
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H360
Hazard InformationBack Directory
[Uses]

Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer[1].
[References]

[1] Festuccia C, et al. Ozarelix, a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Prostate. 2010 Sep 1;70(12):1340-9. DOI:10.1002/pros.21169
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