| Identification | Back Directory | [Name]
Benzoic acid, 2-([1,1′-biphenyl]-3-ylamino)-4-fluoro- | [CAS]
2996821-30-6 | [Synonyms]
Benzoic acid, 2-([1,1′-biphenyl]-3-ylamino)-4-fluoro- | [Molecular Formula]
C19H14FNO2 | [MOL File]
2996821-30-6.mol | [Molecular Weight]
307.32 |
| Chemical Properties | Back Directory | [Boiling point ]
479.4±45.0 °C(predicted) | [density ]
1.293±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.66±0.36(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells[1]. | [References]
[1] Ahmed Fnaiche, et al. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg Med Chem Lett. 2023 Oct 15:95:129488. DOI:10.1016/j.bmcl.2023.129488 |
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