| Identification | Back Directory | [Name]
1(4H)-Quinolineacetic acid, 3-[(2,3-dichlorophenyl)methyl]-6-methoxy-4-oxo-, potassium salt (1:1) | [CAS]
3009908-95-3 | [Synonyms]
WJ-39
1(4H)-Quinolineacetic acid, 3-[(2,3-dichlorophenyl)methyl]-6-methoxy-4-oxo-, potassium salt (1:1) | [Molecular Formula]
C19H15Cl2NO4.K | [MOL File]
3009908-95-3.mol | [Molecular Weight]
431.33 |
| Hazard Information | Back Directory | [Uses]
WJ-39 is an orally active aldose reductase (AR) inhibitor. WJ-39 improves tubular damage in diabetic nephropathy rats by activating PINK1/Parkin signaling, promoting mitophagy, and attenuating apoptosis[1]. | [References]
[1] Yang L, et al. An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling. Eur J Pharmacol. 2024 Mar 15;967:176376. DOI:10.1016/j.ejphar.2024.176376 |
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