| Identification | Back Directory | [Name]
ESI-08 | [CAS]
301177-43-5 | [Synonyms]
ESI-08
EPAC2,cAMP,ESI08,ESI 08,exchange,proteins,EPAC,Ras,inhibit,EPAC1,ESI-08,Inhibitor
5-Pyrimidinecarbonitrile, 4-cyclohexyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo- | [Molecular Formula]
C20H23N3OS | [MDL Number]
MFCD01313047 | [MOL File]
301177-43-5.mol | [Molecular Weight]
353.48 |
| Chemical Properties | Back Directory | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 100 mg/mL (282.90 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation[1]. | [storage]
4°C, protect from light |
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| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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