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3024860-29-2

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3024860-29-2 Structure

3024860-29-2 Structure

Identification	Back Directory
[Name] Tyk2-IN-18
[CAS] 3024860-29-2
[Synonyms] Tyk2-IN-18
[Molecular Formula] C21H24F2N4O3
[MOL File] 3024860-29-2.mol
[Molecular Weight] 418.44

Chemical Properties	Back Directory
[Boiling point ] 651.5±55.0 °C(predicted)
[density ] 1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 13.33±0.20(predicted)

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[Uses] Tyk2-IN-18 (compound 86) is a potent tyrosine kinase 2 (Tyk2) inhibitor. Tyk2-IN-18 inhibits JAK2-JH2, with an IC50 of ＜10 nM[1][2].
[IC 50] Tyk2 JH2: <10 nM (IC₅₀)
[References] [1] Ram W. Sabnis. Novel Tyrosine Kinase 2 Inhibitors for Treating Autoimmune and Inflammatory Diseases. ACS Med. Chem. Lett. May 16, 2024. [2] Jeffrey Vessels, et al. Tyrosine kinase 2 inhibitors and uses thereof. WO2023250064A1. 2023-12-28.

3024860-29-2 suppliers list

Company Name:	TargetMol Chemicals Inc.
Telephone:	15002134094
Website:	https://www.targetmol.cn/

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