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3026502-95-1

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3026502-95-1 Structure

3026502-95-1 Structure
IdentificationBack Directory
[Name]

WRN inhibitor 8
[CAS]

3026502-95-1
[Synonyms]

WRN inhibitor 8
(S,E)-N-(1-cyclopropyl-3-(methylsulfonyl)allyl)-2-(cyclopropyldifluoromethyl)-4-phenoxypyrimidine-5-carboxamide
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC50 value of 48 nM. WRN inhibitor 8 can be used in cancer research[1].
[References]

[1] Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11.
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