| Chemical Properties | Back Directory | [Boiling point ]
420.4±40.0 °C(predicted) | [density ]
1.37±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/mL
Ethanol: Slightly Soluble: 0.1-1 mg/mL | [form ]
Solid | [pka]
8.14±0.14(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM[1]. | [References]
[1] Wang P, et al. Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists. J Med Chem. 2024 Jan 11;67(1):110-137. |
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