302841-89-0

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302841-89-0 Structure

Identification	Back Directory
[Name] Ro 67-4853
[CAS] 302841-89-0
[Synonyms] Ro 67-4853 Butyl 9H-xanthene-9-carbonylcarbamate (9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester N-(9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester Carbamic acid, N-(9H-xanthen-9-ylcarbonyl)-, butyl ester
[Molecular Formula] C19H19NO4
[MDL Number] MFCD20270618
[MOL File] 302841-89-0.mol
[Molecular Weight] 325.36

Chemical Properties	Back Directory
[Melting point ] 190-194°C
[storage temp. ] Refrigerator
[solubility ] Chloroform, Methanol
[form ] Solid
[color ] White

Safety Data	Back Directory
[Symbol(GHS) ] GHS07,GHS08,GHS09
[Signal word ] Danger
[Hazard statements ] H302-H361-H372-H410
[Precautionary statements ] P201-P264-P280-P301+P330+P331-P312

Hazard Information	Back Directory
[Uses] Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptor (1,2). Ro 67-4853 exhibits activity at all group I receptors such as human and rat mGlu1/mGlu5. It also enhance glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors.
[IC 50] Rat mGluR1a: 7.16 (pEC₅₀)
[storage] Store at RT

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