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3029365-95-2

3029365-95-2 Structure

3029365-95-2 Structure
IdentificationBack Directory
[Name]

4-Thiazolecarboxylic acid, 2-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-5-[3-(4-iodophenoxy)propyl]-, ethyl ester
[CAS]

3029365-95-2
[Synonyms]

4-Thiazolecarboxylic acid, 2-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-5-[3-(4-iodophenoxy)propyl]-, ethyl ester
[Molecular Formula]

C32H29IN4O4S2
[MOL File]

3029365-95-2.mol
[Molecular Weight]

724.63
Chemical PropertiesBack Directory
[density ]

1.561±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

8.88±0.70(predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs[1].
[References]

[1] Chun-Wa Chung, et al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323. DOI:10.1021/acschembio.0c00266
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