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3032196-65-6

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3032196-65-6 Structure

3032196-65-6 Structure
IdentificationBack Directory
[Name]

TEAD-IN-10
[CAS]

3032196-65-6
[Synonyms]

TEAD-IN-10
[Molecular Formula]

C15H14F3NO
[MOL File]

3032196-65-6.mol
[Molecular Weight]

281.27
Chemical PropertiesBack Directory
[Boiling point ]

387.0±42.0 °C(predicted)
[density ]

1.299±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

-1.68±0.40(predicted)
Hazard InformationBack Directory
[Uses]

TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].
[IC 50]

TAED1: 14 nM (IC50); TAED2: 179 nM (IC50); TAED3: 4 nM (IC50)
[References]

[1] Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15
3032196-65-6 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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