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PKMYT1-IN-1 (Compound 1) is an inhibitor for membrane-associated tyrosine and threonine kinase (PKMYT1), with an IC50 of 8.8 nM. PKMYT1-IN-1 inhibits proliferation of tumor cell HCC1569 with IC50 of 42 nM[1]. | [IC 50]
PKMYT1: 8.8 nM (IC50) | [References]
[1] Zhu D, et al., Membrane-associated tyrosine and threonine kinase inhibitor and use thereof. WO2024061343A1. |
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