| Chemical Properties | Back Directory | [Boiling point ]
640.051±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.406±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
8.259±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
PPO-IN-10 (Compound 4) is a 2-phenylpyridine derivative of pyrrolidone. PPO-IN-10 inhibits protoporphyrinogen IX oxidase (PPO). PPO-IN-10 leads to the formation of photosensitive protoporphyrin IX and the death of weed leaves. PPO-IN-10 can be used in the research of developing new PPO herbicides[1]. | [in vivo]
PPO-IN-10 (18.75 and 9.375 g ai/ha, Spray Administration) shows higher herbicidal activity at low doses but lower than the positive controls FLU and SAF[1].
| Animal Model: | EC,DS,LP,AR,AT and MS | | Dosage: | 18.75 and 9.375 g ai/ha | | Administration: | Spray Administration | | Result: | Compounds 4d, 4f, and 4l were better than that of the positive control ACI. |
| [References]
[1] Zhang M, Cai H, Pang C, et al. Design, Synthesis, and Herbicidal Evaluation of Pyrrolidinone-Containing 2-Phenylpyridine Derivatives as Novel Protoporphyrinogen Oxidase Inhibitors[J]. Journal of Agricultural and Food Chemistry, 2024. |
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