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3036553-83-7

3036553-83-7 Structure

3036553-83-7 Structure
IdentificationBack Directory
[Name]

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-
[CAS]

3036553-83-7
[Synonyms]

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-
[Molecular Formula]

C29H24N6O4
[MOL File]

3036553-83-7.mol
[Molecular Weight]

520.54
Chemical PropertiesBack Directory
[density ]

1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

10.72±0.40(predicted)
Hazard InformationBack Directory
[Uses]

WIZ degrader 7 (Example 16) is a WIZ degrader with an IC50 value of < 0.01 μM. WIZ degrader 7 can be used to investigate sickle cell disease (SCD) and thalassemia[1].
[References]

[1] Thomas J, et al. Compounds and their use for treatment of hemoglobinopathies. WO2024097932A1.2024-05-10.
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