| Identification | Back Directory | [Name]
c-Fms-IN-15 | [CAS]
3047930-25-3 | [Synonyms]
c-Fms-IN-15
1,5-Naphthyridine-4-carboxamide, N-methyl-2-[4-[[[[4-(4-methyl-1-piperazinyl)-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]- | [Molecular Formula]
C29H28F3N7O2 | [MOL File]
3047930-25-3.mol | [Molecular Weight]
563.57 |
| Chemical Properties | Back Directory | [Boiling point ]
661.4±55.0 °C(predicted) | [density ]
1.364±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
12.72±0.46(predicted) |
| Hazard Information | Back Directory | [Uses]
c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with the IC50 of 563 nM[1]. | [References]
[1] Anusha Sebastian, et al. Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase. Eur J Med Chem. 2024 Aug 5:274:116557. DOI:10.1016/j.ejmech.2024.116557 |
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TargetMol
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