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305336-82-7

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305336-82-7 Structure

305336-82-7 Structure
IdentificationBack Directory
[Name]

ANGIOTENSIN I CONVERTING ENZYME 2, (ACE-2) SUBSTRATE
[CAS]

305336-82-7
[Synonyms]

MCA-APK(DNP)
MCA-ALA-PRO-LYS(DNP)-OH
Angiotensin I Converting Enzyme 2
ANGIOTENSIN I CONVERTING ENZYME 2, (ACE-2) SUBSTRATE
N-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine
L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-
[Molecular Formula]

C32H36N6O12
[MDL Number]

MFCD08459451
[MOL File]

305336-82-7.mol
[Molecular Weight]

696.66
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Yellow to orange
[Sequence]

Mca-Ala-Pro-Lys(Dnp)-OH
Hazard InformationBack Directory
[Uses]

Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung[1][2].
[References]

[1] Liu J, Ji H, et al. Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent. Biol Sex Differ. 2010;1(1):6. Published 2010 Nov 5. DOI:10.1186/2042-6410-1-6
[2] Liang Y, et al. Urinary angiotensin converting enzyme 2 increases in patients with type 2 diabetic mellitus. Kidney Blood Press Res. 2015;40(2):101-110. DOI:10.1159/000368486
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