| Identification | More | [Name]
4-METHOXY-2-(TRIFLUOROMETHYL)PHENYLBORONIC ACID | [CAS]
313546-16-6 | [Synonyms]
4-METHOXY-2-(TRIFLUOROMETHYL)BENZENEBORONIC ACID
4-METHOXY-2-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
4-METHOXY-2-(TRIFLUOROMETHYL)PHENYLBORO&
4-METHOXY-2-(TRIFLUOROMETHYL)PHENYLBRONIC ACID | [Molecular Formula]
C8H8BF3O3 | [MDL Number]
MFCD03095346 | [Molecular Weight]
219.95 | [MOL File]
313546-16-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
168-172 °C | [Boiling point ]
314.1±52.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
powder to crystal | [pka]
8.54±0.58(Predicted) | [color ]
White to Almost white | [InChI]
1S/C8H8BF3O3/c1-15-5-2-3-7(9(13)14)6(4-5)8(10,11)12/h2-4,13-14H,1H3 | [InChIKey]
ZBCRZEJNAADYKG-UHFFFAOYSA-N | [SMILES]
COc1ccc(B(O)O)c(c1)C(F)(F)F | [CAS DataBase Reference]
313546-16-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Reactant involved in:
- Synthesis of pyrazine derivatives as corticotropin releasing factor-1 receptor antagonists
- C-H functionalization of quinones
- Phenyl-purine-carbonitrile derivative synthesis as cathepsin S inhibitors
- Synthesis of chiral bicyclooctadiene-based ligands
- Synthesis of corticotropin-releasing factor-1 antagonists
| [Uses]
Reactant involved in:• ;Synthesis of pyrazine derivatives as corticotropin releasing factor-1 receptor antagonists1• ;C-H functionalization of quinones1• ;Phenyl-purine-carbonitrile derivative synthesis as cathepsin S inhibitors2• ;Synthesis of chiral bicyclooctadiene-based ligands3• ;Synthesis of corticotropin-releasing factor-1 antagonists4 | [Uses]
suzuki reaction | [Synthesis]
Three.0 g (8.85 mmol) of potassium phosphate heptahydrate, 1.50 g (5.90 mmol) of bis(boronic acid) pinacol ester B2(pin)2, 12 mg
(0.015 mmol) Xphos-Pd-G2 and 4 mg (0.008 mmol)
Xphos were added sequentially to the reaction vial, 6 mL of ethanol was ad |
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