ChemicalBook--->CAS DataBase List--->3160-91-6

3160-91-6

3160-91-6 Structure

3160-91-6 Structure
IdentificationBack Directory
[Name]

Moroxydine hydrochloride
[CAS]

3160-91-6
[Synonyms]

virustat
spenitol
virusmin
flumidin
Virus spirit
Moroxydine hyd
MOROXYDINE HCL
abobhydrochloride
TIMTEC-BB SBB009855
Moroxydine Hydrochlo
Moroxydine hydrochlorid
MOROXYDINE HYDROCHLORIDE
MoroxydineHydrochloride>
MORPHOLINO-BIUANIDE HYDROCHLORIDE
MORPHOLINO-BIGUANIDE HYDROCHLORIDE
Moroxydine hydrochloride USP/EP/BP
Moroxydine hydrochloride Solution, 100ppm
1-morpholinocarbonimidoylguanidine hydrochloride
n-amidino-4-morpholinecarboxamidinmonohydrochloride
1,1-anhydrobis(beta-hydroxyethyl)-biguanidhydrochloride
N-CarbaMiMidoylMorpholine-4-carboxiMidaMide hydrochloride
Guanidine,N-(amino-4-morpholinylmethyl)-, hydrochloride (1:1)
N-(AMINOIMINOMETHYL)-4-MORPHOLINECARBOXIMIDAMIDE HYDROCHLORIDE
n-(aminoiminomethyl)-4-morpholinecarboximidamidmonohydrochloride
n(sup1),n(sup1)-anhydrobis(beta-hydroxyethyl)biguanidehydrochloride
4-Morpholinecarboximidamide, N-(aminoiminomethyl)-,monohydrochloride
N-(aminoiminomethyl)-4-morpholinecarboximidamide,hydrochloride (1:1)
N-Carbamimidoylmorpholine-4-carboximidamide hydrochloride[ABOB Hydrochloride
[EINECS(EC#)]

221-612-6
[Molecular Formula]

C6H14ClN5O
[MDL Number]

MFCD00012798
[MOL File]

3160-91-6.mol
[Molecular Weight]

207.66
Chemical PropertiesBack Directory
[Melting point ]

211-214 °C(lit.)
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

DMSO (Very Slightly, Heated), Water (Slightly)
[form ]

Solid
[color ]

Off-White
[Merck ]

14,6272
[InChI]

InChI=1S/C6H13N5O.ClH/c7-5(8)10-6(9)11-1-3-12-4-2-11;/h1-4H2,(H5,7,8,9,10);1H
[InChIKey]

FXYZDFSNBBOHTA-UHFFFAOYSA-N
[SMILES]

N1(CCOCC1)C(=N)NC(=N)N.Cl
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-37/39
[WGK Germany ]

3
[RTECS ]

QD9815000
[HS Code ]

2934.99.4700
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Originator]

Grippe,Nissin
[Uses]

Moroxydine hydrochloride is an antiviral used against a number of RNA and DNA viruses.
[Manufacturing Process]

43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water, and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4- morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization from methanol. The salt may be converted into the base by adding equivalent of any basic compound (triethylamine, sodium bicarbonate and so on).
In practice it is usually used as hydrochloride.
[Therapeutic Function]

Antiviral
[General Description]

Determination of moroxydine hydrochloride in Gan Mao Qing capsules by derivative spectrophotometric signal multiplier method has been reported. Therapeutical efficiency of moroxidine hydrochloride against herpes virus induced keratoconjunctivitis has been evaluated by immunofluorescence techniques.
[storage]

Store at -20°C
[References]

[1] Patent: CN105481797, 2016, A. Location in patent: Paragraph 0039; 0040
Spectrum DetailBack Directory
[Spectrum Detail]

Moroxydine hydrochloride(3160-91-6)1HNMR
Moroxydine hydrochloride(3160-91-6)IR
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