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31752-99-5

31752-99-5 Structure

31752-99-5 Structure
IdentificationMore
[Name]

(-)-Corey lactone 4-phenylbenzoate alcohol
[CAS]

31752-99-5
[Synonyms]

(3AALPHA,4ALPHA,5BETA,6AALPHA)-(-)-HEXAHYDRO-4-(HYDROXYMETHYL)-2-OXO-2H-CYCLOPENTA[B]FURAN-5-YL 1,1'-BIPHENYL-4-CARBOXYLATE
(-)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL
(3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one, 99%
(-)-COREY LACTONE 4-PHENYLBENZOATE
4-Phenylbenzoyl corey lactone
(-)-COREY LACTONE 4-PHENYLBENZOATE ALCOHOL 99%
(-)-Corey lactone 4-phenylbenzoate alcohol
(3aalpha,4alpha,5beta,6aalpha)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate
(3aR,4S,5R,6aS)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate
(-)-Corey lactone, 4-PBP
(-)-Corey lactone 5-(4-phenylbenzoate, (-)-Corey lactone, 4-phenylbenzoate alcohol, (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1μ-biphenyl-4-carboxylate
(-)-Corey lactone 5-(4-phenylbenzoate, (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1μ-biphenyl-4-carboxylate
(-)-Corey lactone, 4-phenylbenzoate alco-hol,99%
[EINECS(EC#)]

608-667-5
[Molecular Formula]

C21H20O5
[MDL Number]

MFCD00078077
[Molecular Weight]

352.38
[MOL File]

31752-99-5.mol
Questions And AnswerBack Directory
[Description]

(-)-Corey lactone 4-phenylbenzoate alcohol is one of the isomers of biphenyl-4-formylcorilactone, which can be used for the synthesis of prostaglandins. Prostaglandins are a class of important endogenous physiologically active substances, important mediators of various physiological processes, and have high pharmacological activity. Clinically, prostaglandins are all artificially synthesized.
Chemical PropertiesBack Directory
[Appearance]

Off-White to Pale Yellow Solid
[Melting point ]

131-132 °C(lit.)
[alpha ]

-89 º (c=1, CHCl3)
[Boiling point ]

446°C (rough estimate)
[density ]

1.1818 (rough estimate)
[refractive index ]

1.5400 (estimate)
[storage temp. ]

2-8°C
[solubility ]

Chloroform, Ethyl Acetate
[form ]

Solid
[pka]

14.79±0.10(Predicted)
[color ]

Off-White to Pale Yellow
[Optical Rotation]

[α]20/D 87°, c = 1 in chloroform
[Water Solubility ]

insoluble
[Usage]

Key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2a
[BRN ]

1294692
[InChI]

1S/C21H20O5/c22-12-17-16-10-20(23)25-18(16)11-19(17)26-21(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,16-19,22H,10-12H2/t16-,17-,18+,19-/m1/s1
[InChIKey]

SZJVIFMPKWMGSX-UHFFFAOYSA-N
[SMILES]

OC[C@H]1[C@@H](C[C@@H]2OC(=O)C[C@H]12)OC(=O)c3ccc(cc3)-c4ccccc4
[CAS DataBase Reference]

31752-99-5(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[REACH Registrations]

Active
[HS Code ]

29322090
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Pale Yellow Solid
[Uses]

(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF.
Spectrum DetailBack Directory
[Spectrum Detail]

(-)-Corey lactone 4-phenylbenzoate alcohol(31752-99-5)MS
(-)-Corey lactone 4-phenylbenzoate alcohol(31752-99-5)1HNMR
(-)-Corey lactone 4-phenylbenzoate alcohol(31752-99-5)IR1
(-)-Corey lactone 4-phenylbenzoate alcohol(31752-99-5)IR2
(-)-Corey lactone 4-phenylbenzoate alcohol(31752-99-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

(-)-Corey lactone 4-phenylbenzoate alcohol, 99%(31752-99-5)
[Sigma Aldrich]

31752-99-5(sigmaaldrich)
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