| Identification | Back Directory | [Name]
R 170591 | [CAS]
317846-22-3 | [Synonyms]
R 170591
HE066500
HE-066500
HE 066500
JNJ 2408068
JNJ2408068,JNJ 2408068
2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol
3-Pyridinol, 2-[[2-[[1-(2-aminoethyl)-4-piperidinyl]amino]-4-methyl-1H-benzimidazol-1-yl]methyl]-6-methyl- | [Molecular Formula]
C22H30N6O | [MDL Number]
MFCD18782600 | [MOL File]
317846-22-3.mol | [Molecular Weight]
394.51 |
| Chemical Properties | Back Directory | [Boiling point ]
658.3±65.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.19±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1]. | [References]
[1] Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31. DOI:10.1016/j.antiviral.2003.07.002 |
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Website: |
www.chemicalbook.com/showsupplierproductslist927327/0_en.htm |
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