| Identification | Back Directory | [Name]
H-LEU-LEU-OH | [CAS]
3303-31-9 | [Synonyms]
LL
LEU-LEU
NSC 89185
Leu-Leu-OH
L-LEU-L-LEU
H-LEU-LEU-OH
L-Leu-L-Leu-OH
leu-leu free base
L-LEUCYL-L-LEUCINE
L-Leucine, L-leucyl-
N-L-leucyl-L-leucine
Leu-Leu-OH≥ 96% (HPLC)
Leu-Leu.HCl|H-Leu-Leu-OH.HCl
-2-Amino-4-methylpentanamido)
(S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanoic acid
(S)-2-[[(S)-2-Amino-4-methylvaleryl]amino]-4-methylvaleric acid
(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoic acid
(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoic acid | [EINECS(EC#)]
221-976-6 | [Molecular Formula]
C12H24N2O3 | [MDL Number]
MFCD00065185 | [MOL File]
3303-31-9.mol | [Molecular Weight]
244.33 |
| Chemical Properties | Back Directory | [Melting point ]
270-272℃ (decomposition) | [Boiling point ]
432.7±30.0 °C(Predicted) | [density ]
1.051±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Methanol (Slightly, Heated), Water (Slightly, Sonicated) | [form ]
Solid | [pka]
3.16±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1 | [InChIKey]
LCPYQJIKPJDLLB-UWVGGRQHSA-N | [SMILES]
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs[1]. | [Definition]
ChEBI: A dipeptide formed from two L-leucine residues. | [Biological Activity]
Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2. | [References]
[1] Matthews DM, et al. Uptake of L-leucyl-L-leucine and glycylsarcosine by hamster jejunum in vitro. Clin Sci (Lond). 1983 Aug;65(2):177-84. DOI:10.1042/cs0650177 |
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