ChemicalBook--->CAS DataBase List--->330456-25-2

330456-25-2

330456-25-2 Structure

330456-25-2 Structure
IdentificationBack Directory
[Name]

Tau Peptide (275-305) (Repeat 2 Domain)
[CAS]

330456-25-2
[Synonyms]

Tau Peptide (275-305) (Repeat 2 Domain)
[Molecular Formula]

C139H239N43O45S
[MOL File]

330456-25-2.mol
[Molecular Weight]

3264.76
Chemical PropertiesBack Directory
[Boiling point ]

2937.0±65.0 °C(Predicted)
[density ]

1.311±0.06 g/cm3(Predicted)
[form ]

Solid
[color ]

White to off-white
[Sequence]

Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-Asp-Leu-Ser-Asn-Val-Gln-Ser-Lys-Cys-Gly-Ser-Lys-Asp-Asn-Ile-Lys-His-Val-Pro-Gly-Gly-Gly-Ser
Hazard InformationBack Directory
[Uses]

Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein[1].
[References]

[1] Dan-Jing Yang, et al. Mercury(II) promotes the in vitro aggregation of tau fragment corresponding to the second repeat of microtubule-binding domain: Coordination and conformational transition. Biopolymers. 2010 Dec;93(12):1100-7. DOI:10.1002/bip.21527
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