| Identification | Back Directory | [Name]
8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER | [CAS]
330589-21-4 | [Synonyms]
NOHLKSJQMSPOTB-YRLDPNHWSA-N
8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER
9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER | [Molecular Formula]
C23H38O5 | [MDL Number]
MFCD01632736 | [MOL File]
330589-21-4.mol | [Molecular Weight]
394.54 |
| Chemical Properties | Back Directory | [Boiling point ]
511.8±50.0 °C(Predicted) | [density ]
1.079±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >30 mg/ml (from PGF2a isopropy; DMSO: >50 mg/ml (from PGF2a isopropy; Ethanol: >50 mg/ml (from PGF2a isopropy; PBS pH 7.2: <50 μg/ml (from PGF2a isopropy | [pka]
13.79±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids. | [Uses]
8-Iso prostaglandin E2 isopropyl ester is a more lipophilic form of the free acid, 8-iso Prostaglandin E2. |
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